ࡱ> [ c&bjbj  4pa!\pa!\c  L>8(7,c7777777$;=N777!!!7!7!!12@x> 2780>8+2 >T 0 >022 >a3H{Z@!4Ig{{{77!"{{{>8 >{{{{{{{{{ > L: Clinical chemistry 456 Spring 2009 InstructorOffice and HoursLecture Dr. Tilly Wang 310.243.3388 NSM B304, twang@csudh.edu Tue and Thu, 4.00-6.00pmTTH 11.30-12.45 AM NSM C221  Prerequisites for the course: Biochemistry and lab and Organic Chemistry and Lab Introduction Lectures on application of general chemistry and biochemistry in clinical chemistry, quality control and statistic analysis of clinical chemistry lab data. This course will introduce concepts and themes that you will encounter in future clinical research and hospital; a solid knowledge of the topics covered in this course will be the foundation for your future studies. Student outcomes At the conclusion of the course, student will demonstrate understanding clinical chemical concepts and their applications to clinical study. a. Recognize the inter-relationships between various organ systems in health and in selected disease processes.b. Correlate laboratory data with clinical data in patient evaluation. c. Assess significance of data involving patient variable, and other non-analytical variables. Textbook Michael L. Bishop, Edward P. Fody and Larry Schoeff. Clinical Chemistry Lecture notes references Michael L. Bishop, Edward O. Fody and Larry Schoeff. Clinical Chemistry Appleton and Langes. Outline review clinical chemistry www.bertholf.net/rlb/Lectures/Lectures/ Clinical laboratory science review  HYPERLINK "http://www.google.com" www.google.com Materials needed Ability to access the blackboard http://toro7.csudh.edu/webapps/portal/frameset.jsp  HYPERLINK "http://www.csudh.edu/acresmgt/classched/Fa09/fa09che.htm" http://www.csudh.edu/acresmgt/classched/Fa09/fa09che.htm Communication using campus E-mail address one 6 function calculator Safety glasses or goggles BLACKBOARD I will be using Blackboard on the web to "enhance" this class. You will find class notes, announcement and homework assignments etc. on Black board site. The Clinical Chemistry course will deal with the following topics: DateTopicAssignmentJan.27IntroductionBishop et. al. Chap 3, pp.91-9629Spectrophotometer Chap 4, pp.77-82Feb3Laboratory StatisticsChap. 3, pp.49-555Quality Controlpp.70-8210Quality Control12Amino acids and proteinsChap. 817proteins and electrophoresisChap. 819Proteomics and case study24Exam126Carbohydrate BiochemistryChap.11March3Glucose, Diabetes5Hypoglycemia, Glucose Methodologies10electrolytesChap. 1312electrolytesChap. 1317electrolytesChap. 1319Blood gases, pHChap. 1424Blood gases, pHChap. 1426Introduction to EnzymesChap. 1031Spring breakApril2Spring break7Exam29Introduction to Enzymes14Immunoassay-antibodies, antigensChap. 616Immunoassay systems21Renal FunctionChap. 2423Renal Function28Liver FunctionChap. 2230Liver FunctionMay5Pancreatic functionChap. 257Pancreatic Enzymes12Exam314Student Presentations19Student Presentations21Assignments should be read before class.Presentation: Working with a partner. A short paper (4-5 pages) on a topic in breast cancer is worth 10% of your grade. The topic should be something we haven't covered or won't cover in class or a more in-depth review of some aspect of disease or a new test. For example, the history of breast cancer from your own ethnic group. It must be typed, double-spaced and follow approved American Psychological Association (APA) format for footnotes ( http://owl.english.purdue.edu/owl/resource/560/01/ ). A minimum of five current sources (less than five years) should be used. Sources should include both books and periodicals. One of the sources should be from the internet/WWW (with appropriate citation). Guidelines to the paper and presentation: Introduction (to the topic being reviewed) including a summary of the history of research on this topic. A review of the classic and current literature in the topic field, covering the major sub-topics and commenting on the state of knowledge in this field. Summary, Conclusions, and an analysis of possible further directions in this field. February 24 Topic approved by instructor. March 24 Outline including sources April 16 Rough draft due May 7 Final draft due/ Presentation Academic Integrity Statement A university is a community of learners bonded together by the search for knowledge; the pursuit of personal, social, cultural, physical, and intellectual development; and the desire for the liberating effects of an advanced education. ɫ, Dominguez Hills (CSUDH) has a culture--an academic culture--shared with other universities and colleges across the nation. Integral to that culture is a set of values such as academic freedom, dedication to teaching and learning, diversity, civility toward others, and academic integrity. Academic integrity is of central importance in the university community and involves committed allegiance to the values, the principles, and the code of behavior held to be central in that community. Integrity concerns honesty and implies being truthful, fair, and free from lies, fraud and deceit. Course requirements Grading The grade in this course is assigned largely on the basis of points accumulated of a total of approximately 650 points in the following categories: ActivityPoint PossibleExam1100Exam 2100Exam 3100Quizzes100laboratory150Student presentations100Total650 The instructor may make minor changes to the total number of points as necessary. The class will not be curved. The student should be aware of their scores they obtain and the grade they will get by calculating the results for themselves. The instructor will provide details of the requirements for specific letter grades as the semester progresses. Plus and minus grades will be issued in this course. GradePercentagesGradePercentagesA100-91A-90-89B+88-87B86-81B-80-79C+78-77C76-71C-70-69D+68-67D66-60F59-0 Examinations and Quizzes Students are required to take quizzes and examinations designed to measure each individuals understanding of the course objectives cited above, which will include both problem solving and essay responses. Students are required to take 3 exams and a final examination administered on the following dates: Make-up exams: Instructor must be notified within 24 hours of missed exam if student has to take a make-up exam. Exam should be made up within 3 days. If you are absent for a unit exam or weekly quiz, it is your responsibility to schedule a time for a make-up. Both exams and quizzes may include material from the textbook that is not explicitly discussed in lecture. Attendance requirements Students are required to conduct themselves in a professional manner during class. Cell phones, pagers and other electronic devices must be turned off during lecture. Late arrivals, side-discussions and other unprofessional behavior will be addressed at the instructors discretion. There is no recording of attendance. Attendance will be recorded according to their homework and quizzes. Please remember to turn in your homework. If you do not turn in your homework, your grade will be affected. Students returning from absences are advised to copy lecture notes from students in their study group. Study Suggestions Always study illustrations and skim the text before attending lectures. Do as many problems possible in addition to the assigned homework and do them without relying on solution keys. Work additional problems and review for the exams with small study group members. Get help from the University Tutorial Services staff and your instructors in a timely manner. 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